Over-the-counter weight-loss pills

The appeal of losing weight quickly is hard to resist. But do weight-loss pills and products lighten anything but your wallet? And are they safe?

Setting realistic expectations

There's no magic bullet for losing weight. The most effective way to lose weight and keep it off is by eating a healthy low-calorie diet and being more physically active.
Weight-loss pills — prescription drugs, nonprescription drugs, herbal products or other dietary supplements — are all, at best, tools that may help with weight loss. 
But there is relatively little research about these products. The best studied of these are prescription weight-loss drugs.
For example, a 2016 study reviewed 28 long-term trials of prescription drugs for treating obesity. 
The researchers concluded that when a person makes appropriate lifestyle changes, a prescription weight-loss drug increases the likelihood of achieving "clinically meaningful" weight loss within a year.
Clinically meaningful weight loss means you've lost enough weight to lower your risk of heart disease, diabetes and other diseases. 
This is generally defined as 5 percent or more of body weight.
It's important to consider that weight loss achieved in a research setting may be greater than in actual practice. 
Also, possible side effects and adverse reactions to weight-loss pills can affect how well you might do.
It's reasonable to expect that prescription weight-loss pills may be beneficial, but they won't be magical. 
They don't work for everyone, and the benefits may be modest. Researchers know much less about the potential benefits and risks of over-the-counter weight-loss products.

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